Andy Coghlan, «First person treated in milestone stem cell trial», New Scientist, 11 ottobre 2010:
A person with spinal injuries today went down in history as the first to receive a treatment derived from human embryonic stem cells (hESCs). […]
Following endless setbacks and delays in authorising the trial, the patient was treated at the Shepherd Center in Atlanta, Georgia.
Surgeons injected millions of oligodendrocyte progenitor cells grown from hESCs into the injury site through a fine needle, hoping the cells would stimulate nerve growth and re-sheathe nerves damaged through the injury. Injured rats treated with the cells recovered some mobility about a month after being treated.
The hope is that these progenitor cells, codenamed GRNOPC1 cells, will help the patient overcome paralysis resulting from the injury, although the primary objective of the trial is to make sure the treatment is safe. […]